OUR DEVELOPMENT PORTFOLIO

Updated October 2020

Cardiovascular diseases
Diabetes
Cancer
Immune-Inflammatory diseases
Neuropsychiatric diseases

Phase 1

Haematological malignancies

Mcl1 inhibitor

Solid tumors

Mcl1 inhibitor

Haematological malignancies

Bcl2 inhibitor

Haematological malignancies

UCART 19

Haematological malignancies

Cart 19

Solid tumors

Anti PD1xAnti TIM3

Solid tumors

Anti PD1xAnti LAG3

Solid tumors

Anti PD1xAnti LAG3xAnti TIM3

Solid tumors

Anti CD73

Phase 2

Colorectal cancer

Anti EGFR

Lung cancer

Anti cMET

Osteoarthritis

ADAMTS-5 inhibitor

Sjögren disease / Crohn's disease

Anti IL7R

Phase 3

Colorectal cancer, 1st line Combo

Lonsurf

Colorectal cancer, 3rd line Combo

Lonsurf

Chronic heart failure

Omecamtiv mecarbil

Autism

Bumetanide