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The major symptoms of depression are

  • Loss of interest, despondency
  • Loss of energy, increased fatigability
  • Almost constant sadness

Other symptoms may also appear:

  • Changes in psychomotor activity (agitation or slowness)
  • Decreased ability to concentrate
  • Changes in appetite (decrease or increase)
  • Trouble sleeping
  • Recurrent thoughts of death or suicide
  • Inexplicable feelings of guilt
  • Loss of self-confidence or self-esteem